Quarterly report pursuant to Section 13 or 15(d)

Condensed Consolidated Statements of Cash Flows

v3.10.0.1
Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Operating activities    
Net loss $ (150,687) $ (84,178)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 24,264 17,003
Amortization (accretion) of investment premiums (discounts) (1,339) 607
Depreciation and amortization expense 2,254 678
Non-cash interest expense 211 0
Asset retirement obligation accretion expense 32 0
Changes in operating assets and liabilities:    
Prepaid expenses and other current assets (2,339) (1,125)
Other assets (225) 2
Accounts payable 116 (1)
Accrued compensation 3,408 1,574
Accrued research and development expenses (203) 1,402
Other current liabilities 2,063 1,104
Long-term liabilities 92 370
Net cash used in operating activities (122,353) (62,564)
Investing activities    
Purchases of short-term investments (402,621) (152,837)
Maturities of short-term investments 131,983 162,094
Sales of short-term investments 60,037 58,217
Purchases of property and equipment (31,756) (10,535)
Net cash (used in) provided by investing activities (242,357) 56,939
Financing activities    
Proceeds from sale of common stock in underwritten offerings, net 293,290 0
Proceeds from issuance of common stock from "at-the-market" facility, net 47,586 19,206
Proceeds from employee stock awards 18,528 495
Taxes paid related to net share settlement of restricted stock units (7,493) (351)
Principal payments on capital lease obligations (396) 0
Net cash provided by financing activities 351,515 19,350
(Decrease) increase in cash, cash equivalents and restricted cash (13,195) 13,725
Cash, cash equivalents and restricted cash at beginning of period 80,617 48,162
Cash, cash equivalents and restricted cash at end of period 67,422 61,887
Non-cash investing and financing activities    
Property and equipment purchases included in accounts payable and other accrued liabilities 3,973 3,064
Facility lease financing obligations 441 6,215
Property & equipment acquired under capital leases 191 0
Asset retirement cost 88 0
Interest capitalized during construction period for build-to-suit lease transaction 77 133
Supplemental cash flow disclosure    
Cash paid for interest $ 110 $ 0