Quarterly report pursuant to Section 13 or 15(d)

Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited)

v3.20.2
Condensed Consolidated Statements of Changes in Stockholders' Equity (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
Total
Cumulative Effect, Period of Adoption, Adjustment
Cumulative Effect, Period of Adoption, Adjusted Balance
At The Market Offering
Common Stock
Common Stock
Cumulative Effect, Period of Adoption, Adjusted Balance
Common Stock
At The Market Offering
Additional Paid-in Capital
Additional Paid-in Capital
Cumulative Effect, Period of Adoption, Adjusted Balance
Additional Paid-in Capital
At The Market Offering
Accumulated Other Comprehensive (Loss) Income
Accumulated Other Comprehensive (Loss) Income
Cumulative Effect, Period of Adoption, Adjusted Balance
Accumulated Deficit
Accumulated Deficit
Cumulative Effect, Period of Adoption, Adjustment
Accumulated Deficit
Cumulative Effect, Period of Adoption, Adjusted Balance
Beginning balance at Dec. 31, 2018 $ 338,857 $ 364 $ 339,221   $ 5 $ 5   $ 866,541 $ 866,541   $ (340) $ (340) $ (527,349) $ 364 $ (526,985)
Beginning balance (in shares) at Dec. 31, 2018         45,951 45,951                  
Accounting Standards Update [Extensible List] us-gaap:AccountingStandardsUpdate201602Member                            
RSU settlements, net of shares withheld $ (4,575)             (4,575)              
RSU settlements, net of shares withheld, shares         197                    
Issuance of common stock pursuant to employee stock awards 2,898             2,898              
Issuance of common stock pursuant to employee stock awards, shares         159                    
Stock-based compensation expense 12,269             12,269              
Net loss (66,257)                       (66,257)    
Unrealized (loss) gain on available-for-sale securities 378                   378        
Ending balance at Mar. 31, 2019 283,934       $ 5     877,133     38   (593,242)    
Ending balance (in shares) at Mar. 31, 2019         46,307                    
Beginning balance at Dec. 31, 2018 338,857 $ 364 $ 339,221   $ 5 $ 5   866,541 $ 866,541   (340) $ (340) (527,349) $ 364 $ (526,985)
Beginning balance (in shares) at Dec. 31, 2018         45,951 45,951                  
Net loss (212,480)                            
Unrealized (loss) gain on available-for-sale securities 573                            
Ending balance at Sep. 30, 2019 318,442       $ 5     1,057,669     233   (739,465)    
Ending balance (in shares) at Sep. 30, 2019         54,125                    
Beginning balance at Mar. 31, 2019 283,934       $ 5     877,133     38   (593,242)    
Beginning balance (in shares) at Mar. 31, 2019         46,307                    
Issuance of common stock, net of commissions and offering costs, value 7,630             7,630              
Issuance of common stock, net of commissions and offering costs, shares         359                    
RSU settlements, net of shares withheld (2,095)             (2,095)              
RSU settlements, net of shares withheld, shares         120                    
Issuance of common stock pursuant to employee stock awards 1,802             1,802              
Issuance of common stock pursuant to employee stock awards, shares         97                    
Stock-based compensation expense 15,201             15,201              
Net loss (74,328)                       (74,328)    
Unrealized (loss) gain on available-for-sale securities 135                   135        
Ending balance at Jun. 30, 2019 232,279       $ 5     899,671     173   (667,570)    
Ending balance (in shares) at Jun. 30, 2019         46,883                    
Issuance of common stock and pre-funded warrants through underwritten offering, net of offering costs 140,711             140,711              
Issuance of common stock and pre-funded warrants, net of offering costs, shares         6,872                    
Issuance of common stock, net of commissions and offering costs, value       $ 5,000           $ 5,000          
Issuance of common stock, net of commissions and offering costs, shares             327                
RSU settlements, net of shares withheld (25)             (25)              
RSU settlements, net of shares withheld, shares         32                    
Issuance of common stock pursuant to employee stock awards 160             160              
Issuance of common stock pursuant to employee stock awards, shares         11                    
Stock-based compensation expense 12,152             12,152              
Net loss (71,895)                       (71,895)    
Unrealized (loss) gain on available-for-sale securities 60                   60        
Ending balance at Sep. 30, 2019 318,442       $ 5     1,057,669     233   (739,465)    
Ending balance (in shares) at Sep. 30, 2019         54,125                    
Beginning balance at Dec. 31, 2019 290,781       $ 6     1,108,516     220   (817,961)    
Beginning balance (in shares) at Dec. 31, 2019         56,806                    
Issuance of common stock, net of commissions and offering costs, value       22,987           22,987          
Issuance of common stock, net of commissions and offering costs, shares             1,528                
Exercise of pre-funded warrants, shares         57                    
RSU settlements, net of shares withheld (1,395)             (1,395)              
RSU settlements, net of shares withheld, shares         455                    
Issuance of common stock pursuant to employee stock awards 1,330             1,330              
Issuance of common stock pursuant to employee stock awards, shares         94                    
Stock-based compensation expense 12,644             12,644              
Net loss (73,509)                       (73,509)    
Unrealized (loss) gain on available-for-sale securities (16)                   (16)        
Ending balance at Mar. 31, 2020 252,822       $ 6     1,144,082     204   (891,470)    
Ending balance (in shares) at Mar. 31, 2020         58,940                    
Beginning balance at Dec. 31, 2019 290,781       $ 6     1,108,516     220   (817,961)    
Beginning balance (in shares) at Dec. 31, 2019         56,806                    
Net loss (225,313)                            
Unrealized (loss) gain on available-for-sale securities 307                            
Ending balance at Sep. 30, 2020 353,935       $ 8     1,396,674     527   (1,043,274)    
Ending balance (in shares) at Sep. 30, 2020         77,220                    
Beginning balance at Mar. 31, 2020 252,822       $ 6     1,144,082     204   (891,470)    
Beginning balance (in shares) at Mar. 31, 2020         58,940                    
Issuance of common stock and pre-funded warrants through underwritten offering, net of offering costs 189,301       $ 1     189,300              
Issuance of common stock and pre-funded warrants, net of offering costs, shares         14,958                    
RSU settlements, net of shares withheld, shares         219                    
Issuance of common stock pursuant to employee stock awards 1,904             1,904              
Issuance of common stock pursuant to employee stock awards, shares         191                    
Stock-based compensation expense 13,948             13,948              
Net loss (77,456)                       (77,456)    
Unrealized (loss) gain on available-for-sale securities 606                   606        
Ending balance at Jun. 30, 2020 381,125       $ 7     1,349,234     810   (968,926)    
Ending balance (in shares) at Jun. 30, 2020         74,308                    
Issuance of common stock, net of commissions and offering costs, value       $ 34,127     $ 1     $ 34,126          
Issuance of common stock, net of commissions and offering costs, shares             2,582                
RSU settlements, net of shares withheld (126)             (126)              
RSU settlements, net of shares withheld, shares         316                    
Issuance of common stock pursuant to employee stock awards 185             185              
Issuance of common stock pursuant to employee stock awards, shares         14                    
Stock-based compensation expense 13,255             13,255              
Net loss (74,348)                       (74,348)    
Unrealized (loss) gain on available-for-sale securities (283)                   (283)        
Ending balance at Sep. 30, 2020 $ 353,935       $ 8     $ 1,396,674     $ 527   $ (1,043,274)    
Ending balance (in shares) at Sep. 30, 2020         77,220