Quarterly report pursuant to Section 13 or 15(d)

Stockholders' Equity - Additional Information (Detail)

v3.22.1
Stockholders' Equity - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended
Apr. 25, 2022
Nov. 30, 2021
Mar. 31, 2022
Dec. 31, 2021
Sep. 30, 2021
Dec. 31, 2020
Nov. 30, 2020
Jun. 30, 2020
Jul. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Authorized capital stock     520,000,000            
Common stock, par value     $ 0.0001 $ 0.0001          
Common stock, shares authorized     500,000,000 500,000,000          
Preferred stock, par value     $ 0.0001            
Preferred stock, shares authorized     20,000,000            
Preferred stock, shares outstanding     0 0          
Stock option granted description terms     the exercise price of an option granted to a 10% shareholder cannot be less than 110% of the estimated fair value of the shares on the date of grant. Options granted generally vest over four years and expire in seven to ten years.            
Ownership percent     10.00%            
Shares of common stock, reserved for issuance     25,371,232            
2014 Equity Incentive Plan                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Shares of common stock, reserved for issuance     20,275,111            
Outstanding options and RSUs     16,401,550            
Aggregate number of awards available for grant to be issued     3,873,561            
Inducement Plan                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Shares of common stock, reserved for issuance     4,002,970            
Outstanding options and RSUs     2,900,995            
Aggregate number of awards available for grant to be issued     1,101,975            
Additional shares of common stock, reserved for issuance         1,500,000   1,500,000    
Restricted Stock Units (RSUs)                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Unrecognized stock-based compensation expense     $ 98,900,000            
Unrecognized stock-based compensation weighted average recognition period     3 years 1 month 6 days            
Restricted Stock Units (RSUs) | From Date Of Grant                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Share based compensation, vesting period     4 years            
Employees And Non Employees                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Share based compensation, vesting period     4 years            
Vested and Unvested Options                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Unrecognized stock-based compensation weighted average recognition period     2 years 10 months 24 days            
Unrecognized stock-based compensation     $ 47,400,000            
Maximum | Employees And Non Employees                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Share based compensation award expiration period     10 years            
Minimum                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Percentage of employees purchase price of common stock     100.00%            
Minimum | 10% Shareholder                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Percentage of employees purchase price of common stock     110.00%            
Minimum | Employees And Non Employees                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Share based compensation award expiration period     7 years            
Underwritten Public Offering | 2019 Warrants                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Warrants outstanding     2,888,526            
Underwritten Public Offering | Warrant                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Number of warrants issued           2,040,816   2,866,961 2,945,026
Number of securities called by each warrant                 1
Warrants, exercise price                 $ 0.0001
Warrants, term 7 years                
Maximum ownership Percentage 9.99%                
Underwritten Public Offering | Warrant | Maximum                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Maximum ownership Percentage 19.99%                
Underwritten Public Offering | Warrant | Minimum                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Prior notice period 61 days                
At The Market Offering | Maximum | Cowen                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Common stock aggregate offering price   $ 100,000,000.0              
Percentage of commission to be paid on gross sales proceeds of common stock sold   3.00%              
2020 ATM Facility | Cowen                  
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                  
Common stock, shares issued     1,319,878            
Common stock average price     $ 15.88            
Proceeds from sale of common stock, gross     $ 21,000,000.0            
Proceeds from sale of common stock, net     20,500,000            
Common stock value remaining to be sold     $ 57,400,000